Thermo Fisher Scientific CD137 (TNFRSF9) Monoclonal Antibody (OTI4G1)
인간 CD137(TNFRSF9) 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot과 Flow cytometry에 사용 가능. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 -20°C 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4G1 |
| Immunogen | Full length human recombinant protein of human TNFRSF9 (NP_001552) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol, 1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells.
CD137 signaling supports the survival and clonal expansion of activated and memory T cells, while regulating myelopoiesis and dendritic cell development. Triggered CD137 induces cytokine release that modulates peripheral monocyte survival. Soluble CD137 may act as a negative regulator in certain immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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