Thermo Fisher Scientific Major Basic Protein (PRG2) Monoclonal Antibody (OTI10D10)
인간 PRG2 단백질을 인식하는 단클론 항체로, Western blot에 적합합니다. 항원은 E. coli에서 발현된 인간 PRG2 아미노산 17-222 영역을 사용했습니다. 액상 형태이며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500 희석
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10D10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 17–222 of human PRG2 (NP_002719) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg.
This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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