
Thermo Fisher Scientific CD2AP Polyclonal Antibody
CD2AP 단백질을 표적하는 Rabbit Polyclonal 항체로, WB 및 IHC에 사용 가능. Mouse 및 Rat 시료에 반응. 동결건조 형태로 제공되며, 4°C 단기 보관 또는 -20°C 장기 보관 권장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 250–300 of mouse CD2AP conjugated to an immunogenic carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage buffer | Whole serum |
| Contains | No preservative |
| Storage conditions | Store at 4°C for short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: CD2AP.
Target Information
This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein interacts with filamentous actin and various membrane proteins through multiple actin-binding sites, SH3 domains, and a proline-rich region. It localizes to membrane ruffles, lipid rafts, and leading cell edges, and is involved in actin remodeling and membrane trafficking during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is linked to susceptibility to glomerular disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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