Thermo Fisher Scientific CD2AP Polyclonal Antibody
CD2AP 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 사용 가능. Mouse와 Rat에 반응하며, 동결건조 형태로 제공. 단기 보관은 4°C, 장기 보관은 -20°C 권장. 세포골격 조절 관련 연구에 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 50–100 of mouse CD2AP conjugated to an immunogenic carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: CD2AP.
Target Information
This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and various cell membrane proteins through multiple actin-binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and leading edges of cells. It is involved in actin remodeling and membrane trafficking during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is associated with susceptibility to glomerular disease.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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