Thermo Fisher Scientific Carbonic Anhydrase III Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.1 µg/mL

-

Immunoprecipitation (IP)

25 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

E. coli-derived recombinant human Carbonic Anhydrase III/CA3 Ala2-Lys260 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Carbonic Anhydrase III,uniProtId:P07451-1,ncbiNodeId:9606,antigenRange:2-260,antigenLength:260,antigenImageFileName:PA5-47265_Carbonic_Anhydrase_III_P07451-1_Goat.svg,antigenImageFileNamePDP:PA5-47265_Carbonic_Anhydrase_III_P07451-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2609648

Product Specific Information

In direct ELISAs, approximately 5% cross-reactivity with recombinant human (rh) CA1, rhCA2, rhCA4, rhCA9, rhCA10, rhCA13 and rhCA14 is observed.

Reconstitute at 0.2 mg/mL in sterile PBS.

Target Information

Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10. 3 kb and contains seven exons and six introns.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.