Thermo Fisher Scientific ARS2 Polyclonal Antibody
ARS2 단백질을 인식하는 Thermo Fisher Scientific의 산양 폴리클로날 항체. Western blot 및 IHC(P) 검증 완료. 인간, 마우스, 랫트 반응성. 액상 형태, 0.5 mg/mL 농도. 연구용으로 miRNA 처리 및 세포 주기 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-DPRAIVEYRDLDAPD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933711 |
Product Specific Information
- This antibody is expected to recognize all reported isoforms (NP_056992.4; NP_001122324.1; NP_001122325.1; NP_001122326.1).
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation.
Contributes to the stability and delivery of capped primary miRNA transcripts to the processing complex containing DGCR8 and DROSHA, playing a role in RNA-mediated gene silencing by miRNAs.
Binds capped RNAs (m7GpppG-capped RNA) via interaction with NCBP1/CBP80 component of the CBC complex.
Involved in cell cycle progression at S phase.
Does not directly confer arsenite resistance but modulates arsenic sensitivity.
Independently promotes neural stem cell self-renewal by binding the SOX2 promoter and positively regulating its transcription.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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