Thermo Fisher Scientific BCL2A1 Polyclonal Antibody
Thermo Fisher Scientific의 BCL2A1 Polyclonal Antibody는 Rat 시료에 반응하며 Western Blot에 적합합니다. Goat에서 유래한 IgG 항체로, 비결합형 액상 형태이며 0.5 mg/mL 농도를 가집니다. 세포사멸 관련 단백질 연구에 유용하며 NF-kB 경로 관련 연구에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.3 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-QKEVEKNLKPYLDD. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933716 |
Product Specific Information
- This antibody may cross-react with the almost identical proteins A1b (GeneID 12045) and A1d (GeneID 12047).
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Bcl-2 related Protein A1 is a member of the BCL-2 protein family. These proteins form hetero- or homodimers and act as anti- and pro-apoptotic regulators involved in various cellular processes such as embryonic development, homeostasis, and tumorigenesis.
The protein encoded by this gene reduces the release of pro-apoptotic cytochrome c from mitochondria and blocks caspase activation.
It is a direct transcription target of NF-kappa B in response to inflammatory mediators and is up-regulated by extracellular signals such as GM-CSF, CD40, phorbol ester, TNF, and IL-1. This suggests a cytoprotective function essential for lymphocyte activation and cell survival.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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