Thermo Fisher Scientific TAF10 Monoclonal Antibody (23TA-1H8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunocytochemistry (ICC/IF)

1:2,000

-

Flow Cytometry (Flow)

1:100

-

Product Specifications

Species Reactivity

Human, Non-human primate, Rat

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

23TA-1H8

Immunogen

Synthetic peptide coupled to ovalalbumin aa 1 to 20 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TAF10,uniProtId:Q12962-1,ncbiNodeId:9606,antigenRange:1-20,antigenLength:218,antigenImageFileName:MA3-069_TAF10_Q12962-1_House_mouse.svg,antigenImageFileNamePDP:MA3-069_TAF10_Q12962-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

ascites

Contains

0.05% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2637137

Product Specific Information

MA3-069 detects TAF10 from human, rat, and non-human primate samples. MA3-069 does not detect the TAF10 in mouse samples

MA3-069 has been successfully used in Western blot, immunofluorescence and flow cytometry applications.

The MA3-069 immunogen is the synthetic peptide coupled to ovalalbumin aa 1 to aa 20.

Target Information

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.