Thermo Fisher Scientific SLUG Polyclonal Antibody
Human SLUG 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 적합. KLH 결합 합성 펩타이드(1-30 aa)로 면역화됨. 2.0 mg/mL 농도의 액상 형태로 제공되며, PBS buffer 및 sodium azide 포함. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 1–30 amino acids from the N-terminal region of human SLUG |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.0 mg/mL |
| Purification | Size-exclusion, Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2191883 |
Product Specific Information
This antibody is predicted to react with bovine, mouse, and rat based on sequence homology.
Target Information
Slug, a member of the Snail family of C2H2-type zinc finger transcription factors, is involved in epithelial-mesenchymal transitions and neural tube formation during vertebrate embryogenesis. Slug transcription can be induced by growth factors such as FGF, BMP, and TGF-beta. Once expressed, Slug binds E-box regions of promoters and represses transcription of genes such as E-cadherin and Claudin-1. Its expression in breast, esophageal, and colorectal carcinomas is correlated with poor prognosis. Additionally, Slug protects hemopoietic progenitor cells from radiation-induced apoptosis by repressing p53-mediated transcription of Puma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-11922_SLUG_O43623-1_Rabbit.svg, PA5-11922_SLUG_O43623-1_Rabbit_PDP.jpeg)
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