Thermo Fisher Scientific CD51 Polyclonal Antibody
Thermo Fisher Scientific의 CD51 폴리클로날 항체는 인간 Integrin Alpha V를 표적으로 하는 연구용 항체로, WB 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. -20°C에서 보관하며 ProClin 300을 함유합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 5–20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein Integrin Alpha V (amino acids 560–744 of the target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903708 |
Target Information
ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain.
The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, which combine with multiple integrin beta chains to form different integrins.
Among the known associating beta chains (β1, β3, β5, β6, and β8), each interacts with extracellular matrix ligands. The αVβ3 integrin, also known as the Vitronectin receptor (VNR), is one of the most studied.
Integrins are involved in adhesion and signal transduction. The ITGB3 protein encodes integrin beta chain β3, found along with the alpha IIb chain in platelets.
Integrins participate in cell adhesion and cell-surface mediated signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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