Thermo Fisher Scientific Phospho-TGFBR2 (Ser553) Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100–1:500

Product Specifications

Product Specific Information

Antibody detects endogenous levels of TGFBR2 only when phosphorylated at Ser553.

Target Information

Transforming Growth Factor, beta receptor 2 (TGFBR2; also known as AAT3, FAA3, MFS2, RIIC, LDS1B, LDS2B, TAAD2, TGFR-2, TGFbeta-RII) is a member of the TGF-beta family of receptor serine/threonine kinases involved in the regulation of cell proliferation.
Mitochondrial ATP synthase catalyzes ATP synthesis utilizing an electrochemical proton gradient across the inner membrane during oxidative phosphorylation. It consists of two multi-subunit complexes: the soluble catalytic core (F1) and the membrane-spanning proton channel (Fo). The catalytic portion comprises five different subunits (α, β, γ, δ, ε) with a stoichiometry of 3α, 3β, and one each of the others. The proton channel includes three main subunits (a, b, c).
TGFBR2 encodes the γ subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. A pseudogene is located on chromosome 14.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.