Thermo Fisher Scientific BRMS1 Recombinant Rabbit Monoclonal Antibody (5Y8J3)
BRMS1 단백질을 인식하는 토끼 유래 재조합 단클론 항체로, WB, IHC, ELISA에 사용 가능. 인간, 생쥐, 랫트에 반응하며 핵 및 세포질에서 발현되는 단백질 검출에 적합. 고순도의 액상 형태로 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat, Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5Y8J3 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human BRMS1 (Q9HCU9) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911764 |
Product Specific Information
- Target localization: Cytoplasm, Nucleus
- Immunogen sequence:
MPVQPPSKDT EEMEAEGDSA AEMNGEEEES EEERSGSQTE SEEESSEMDD EDYERRRSEC VSEMLDLEKQ FSELKEKLFR ERLSQLRLRL EEVGAERAPE
Target Information
This gene reduces the metastatic potential, but not the tumorigenicity, of human breast cancer and melanoma cell lines.
The encoded protein localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC).
It contains two coiled-coil motifs and several imperfect leucine zipper motifs.
Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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