Thermo Fisher Scientific BAK Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

2.5-5.0 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

2.5-5.0 µg/mL

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from the N-terminus of human Bak protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BAK,uniProtId:Q16611-1,ncbiNodeId:9606,antigenRange:1,antigenLength:211,antigenImageFileName:PA5-16470_BAK_Q16611-1_Rabbit.svg,antigenImageFileNamePDP:PA5-16470_BAK_Q16611-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10984708

Product Specific Information

PA5-16470 targets Bak in IHC (P) and WB applications and shows reactivity with mouse, Hamster, and Human samples.

The PA5-16470 immunogen is a synthetic peptide from the N-terminus of human Bak protein.

Target Information

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.