Thermo Fisher Scientific SIRP gamma Polyclonal Antibody
SIRP gamma 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 등 다양한 연구용에 적합. 인간 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 0.9 mg/mL 농도, 4°C 또는 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1–298 (Q9P1W8) of CD172 gamma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.9 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11153018 |
Product Specific Information
- Recommended positive controls: K562
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
SIRP gamma (CD172g) recognizes a 55 kDa signal regulatory protein belonging to the immunoglobulin gene superfamily.
It is expressed on most T lymphocytes and a subset of B-cells but absent on myeloid cells.
CD172g has a truncated cytoplasmic tail similar to SIRP beta but does not require DAP12 for surface expression.
Like SIRP alpha, CD172g binds to CD47 inducing apoptosis and is involved in negative regulation of receptor tyrosine kinase-coupled signalling.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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