Thermo Fisher Scientific SULT2A1 Polyclonal Antibody
Rabbit polyclonal antibody against human SULT2A1, validated for WB and IHC(P). Recognizes human, mouse, and rat. Affinity-purified with >95% purity. Supplied in PBS with 50% glycerol, 1 mg/mL concentration. For research use only.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human SULT2A1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720348 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
SULT1 sulfotransferases exhibit N-sulfating activities of carcinogenic heterocyclic amines and are selective toward phenols, whereas SULT2 enzymes prefer hydroxysteroids and SULT3 family members are selective for N-substituted aryl and alicyclic compounds.
SULT2A1 catalyzes the sulfonation of procarcinogen xenobiotics, hydroxysteroids, and bile acids, and is highly expressed in adrenal and liver tissues. It plays a role in hepatic cholesterol homeostasis.
SULT2B1 consists of two isoforms, SULT2B1a and SULT2B1b, produced by alternative splicing of their first exons. Both isoforms are highly selective for the sulphation of 3β-hydroxysteroids such as pregnenolone, epiandrosterone, DHEA, and androstenediol. SULT2B1b is expressed in prostate, skin, placenta, and lung.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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