Thermo Fisher Scientific Collagen II Polyclonal Antibody, Biotin
Type II collagen에 특이적인 Biotin 결합 폴리클로날 항체로, Western blot, IHC, ELISA, IP 등에 사용 가능. Rabbit IgG 기반으로 높은 민감도 제공. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용.
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Thermo Fisher Scientific Collagen II Polyclonal Antibody, Biotin
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| ELISA | 1:10,000–1:50,000 |
| Immunoprecipitation (IP) | 1:100 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Collagen Type II from adult human knee cartilage and bovine nasal cartilage |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1956961 |
Product Specific Information
The reactivity of the antibody is greatly diminished under denaturing and reducing conditions.
Target Information
COL2A1 encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type.
Defects in processing chondrocalcin, a calcium-binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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