Thermo Fisher Scientific Caspase 6 Polyclonal Antibody
Caspase 6 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 IHC에 사용 가능. 다양한 종(인간, 마우스, 랫, 햄스터 등)에 반응. 액상 형태로 제공되며 4°C 또는 -20°C에서 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–4 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide mapping to the C-terminus of rat caspase-6 large fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2228294 |
Product Specific Information
PA1-28386 detects Caspase 6 from hamster, rat, mouse, human, ovine, canine, rabbit, and non-human primate samples.
Target Information
Caspases are cysteine proteases expressed as inactive precursors that mediate apoptosis by proteolysis of specific substrates. They cleave after aspartic acid residues.
There are two classes of caspases involved in apoptosis:
- Initiators (activated by receptor cluster) such as Caspase-8 and Caspase-9
- Effectors (activated by mitochondrial permeability transition) such as Caspase-3 and Caspase-7
Activated initiator caspases process effector caspases, leading to cell collapse.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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