Thermo Fisher Scientific Caspase 6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5-4 µg/mL

-

Immunohistochemistry (IHC)

5 µg/ml

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide mapping to the C-terminus of rat caspase-6 large fragment if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Caspase 6,uniProtId:O35397-1,ncbiNodeId:10114,antigenRange:277,antigenLength:277,antigenImageFileName:PA1-28386_Caspase_6_O35397-1_Rabbit.svg,antigenImageFileNamePDP:PA1-28386_Caspase_6_O35397-1_Rabbit_PDP.jpeg,sortOrder:3}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2228294

Product Specific Information

PA1-28386 detects Caspase 6 from hamster, rat, mouse, human, ovine, canine, rabbit, non-human primate samples.

Target Information

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.