Thermo Fisher Scientific Complement C4b/C4c Polyclonal Antibody, FITC
인간 C4b/C4c 보체 단백질을 인식하는 FITC 결합 폴리클로날 항체로, IHC(P) 및 유세포분석에 적합합니다. Rabbit IgG 기반으로 PBS 버퍼에 0.09% sodium azide 포함, 4°C 암소 보관. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific Complement C4b/C4c Polyclonal Antibody, FITC
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | - |
| Flow Cytometry (Flow) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | C4c complement isolated from complement activated human serum |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | Not Determined |
| Purification | IgG fraction |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1956460 |
Product Specific Information
PA1-28407 detects C4c / C4b from human samples.
Antigen retrieval for IHC (P): Proteinase K treatment for 30 minutes at 37°C.
Target Information
This gene encodes the acidic form of complement factor 4, a component of the classical activation pathway. The protein is expressed as a precursor that is cleaved into alpha, beta, and gamma chains before secretion. The trimer serves as a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may release C4 anaphylatoxin, mediating local inflammation. Deficiency is linked to systemic lupus erythematosus and type I diabetes mellitus. The gene is located in the MHC class III region on chromosome 6 and may exist in 1–3 copies depending on haplotype.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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