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Thermo Fisher Scientific 53BP1 Polyclonal Antibody
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53BP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 최적화. 인간 및 생쥐 반응성. 고순도 항원 친화 크로마토그래피 정제. DNA 손상 반응 및 종양 억제 연구용.
- 카탈로그번호
- PA585851
- 판매단위
- pk
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마지막 업데이트 2025. 08. 04. 오전 04:51
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Thermo Fisher Scientific PA585851 53BP1 Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
651,100원VAT 포함 716,210원
Thermo Fisher Scientific · Thermo Fisher Scientific 53BP1 Polyclonal Antibody
Thermo Fisher Scientific 53BP1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:4,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the carboxy-terminus of h53BP1, conjugated to a carrier protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.94 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2792970 |
Product Specific Information
- Keep as concentrated solution.
- Positive Control: HeLa, Neuro 2A, C8D30, NIH-3T3, HaCaT.
- Centrifuge briefly prior to opening the vial.
- Store product as a concentrated solution.
Target Information
53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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