Thermo Fisher Scientific SYP Monoclonal Antibody (OTI2A10), TrueMAB
SYP 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 면역세포염색에 적합합니다. HEK293T 세포에서 발현된 인간 Synaptophysin 단백질을 면역원으로 제작되었습니다. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A10 |
| Immunogen | Full length human recombinant protein of human SYP produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Synaptophysin is a calcium-binding integral membrane glycoprotein found in presynaptic vesicles of nearly all neurons. It has four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting a role in synaptic vesicle endocytosis. Synaptophysin is involved in regulating both short-term and long-term synaptic plasticity and is widely used as a marker for nerve terminals and neuroendocrine tumor differentiation. Mutations in the SYP gene have been associated with X-linked intellectual disability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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