Thermo Fisher Scientific SYP Monoclonal Antibody (OTI2E7), TrueMAB
Synaptophysin 단백질을 인식하는 마우스 단클론 항체로, Western blot과 면역세포염색에 적합합니다. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. 신경 말단 및 신경내분비 종양 연구용으로 활용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E7 |
| Immunogen | Full length human recombinant protein of human GADD45G produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Synaptophysin is a calcium-binding integral membrane glycoprotein localized in presynaptic vesicles of nearly all neurons.
It contains four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting a role in synaptic vesicle endocytosis.
Synaptophysin is involved in regulating both short-term and long-term synaptic plasticity and serves as a widely used marker for nerve terminals and neuroendocrine tumor differentiation.
Mutations in the gene can lead to X-linked mental retardation (type 96).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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