Thermo Fisher Scientific FGR Polyclonal Antibody
Thermo Fisher Scientific의 FGR Polyclonal Antibody는 인간 FGR 단백질을 인식하는 토끼 다클론 항체입니다. Western blot, IHC, ICC/IF에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 완충액에 보관되며 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FGR. Recombinant protein control fragment (Product #RP-95911). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789158 |
Product Specific Information
Immunogen sequence:
VFCKKLEPVA TAKEDAGLEG DFRSYGAADH YGPDPTKARP ASSFAHIPNY SNFSSQAINP GFLDSGTIRG VSGIGVTLFI ALYDYEARTE DDLTFTKGEK FHILNNTEGD WWEARSLSSG KTGCIPSNYV APVDSIQAEE WYFGKIG
Target Information
FGR is a SRC-related kinase present in hematopoietic cells. FGR signals within multiple pathways including the integrin pathway and downstream of chemokine and cytokine receptors.
This protein contains N-terminal sites for myristylation and palmitoylation, a PTK domain, and SH2 and SH3 domains involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs.
It localizes to plasma membrane ruffles and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway.
Infection with Epstein-Barr virus results in the overexpression of this protein.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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