Thermo Fisher Scientific TBX3 Monoclonal Antibody (OTI7C4), TrueMAB
TBX3 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 최적화됨. 인간, 생쥐, 랫드 반응성. 동결건조 형태로 제공되며 PBS buffer에 trehalose 포함. 재구성 및 결합 실험에 적합한 고순도 항체.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7C4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 244–481 of human TBX3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
T-box 3 (TBX3) is a transcriptional repressor belonging to a conserved family of genes sharing the T-box DNA-binding domain. It regulates developmental processes and plays roles in limb, mammary gland, and tumor development. Mutations in TBX3 cause ulnar-mammary syndrome (MIM 181450). Overexpression of TBX3 has been observed in certain breast cancer cell lines and is associated with cell immortalization and osteoblast differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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