Thermo Fisher Scientific Human DR3 Synthetic Peptide
Human DR3 단백질의 N-말단 16개 아미노산 서열에 해당하는 합성 펩타이드로, 항체 차단 실험에 사용 가능. 정제된 액상 형태이며 PBS 완충액에 0.1% BSA 포함. 인간 반응성, -20°C 보관. 연구용으로만 사용.
- 카탈로그번호
- PEP0015
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids at the amino terminus of human DR3.
PEP-0015 can be used as a blocking peptide with polyclonal antibody PA5-19886.
Target Information
DR3 (TNFRSF25) is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in tissues enriched in lymphocytes and may play a role in regulating lymphocyte homeostasis. It has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. Signal transduction is mediated by various death domain-containing adaptor proteins. Knockout studies in mice suggest DR3/TNFRSF25 plays a role in removing self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported, most of which are potentially secreted molecules. Alternative splicing in B and T cells undergoes a programmed change upon T-cell activation, predominantly producing full-length, membrane-bound isoforms involved in controlling lymphocyte proliferation induced by T-cell activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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