Thermo Fisher Scientific Human CXCR6 Synthetic Peptide
Human CXCR6 단백질의 C-말단 20개 아미노산 서열 기반 합성 펩타이드. CXCR6 항체의 차단 실험(Block assay)에 사용 가능. 인간 반응성, 액상 형태, PBS 버퍼에 보관. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 20 amino acids near the carboxy terminus of human Bonzo.
PEP-0016 can be used as a blocking peptide with polyclonal antibody PA5-19888.
Target Information
CD186, also known as CXCR6, is a G protein-coupled chemokine receptor reported to be one of the cellular receptors of HIV and SIV.
CD186 is expressed by NKT cells, various subtypes of T cells with activated and memory phenotypes, and some plasma cells.
It has been reported that mouse liver NK cells, but not naïve or splenic NK cells, express CD186.
The ligand of CD186, CXCL16, is expressed by macrophages, dendritic cells, and liver endothelial cells.
Being highly expressed on NKT cells, CD186 is often used as a proxy marker of this cell subset.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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