Thermo Fisher Scientific GITR (TNFRSF18) Monoclonal Antibody (T9P4G4-D7), PerCP
GITR(TNFRSF18) 단백질을 인식하는 마우스 단클론 항체로 PerCP 형광 표지되어 있습니다. WB, IHC, ELISA 등에 사용 가능하며 25 kDa 단백질 검출에 적합합니다. 482/675 nm의 형광 특성을 가지며 연구용으로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | T9P4G4-D7 |
| Immunogen | Synthetic peptide from the C-terminal of Human Tumor Necrosis Factor Receptor Superfamily, Member 18 |
| Conjugate | PerCP |
| Excitation / Emission Max | 482 / 675 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- A 1:1,000 dilution of MA5-45911 was sufficient for detection of Tumor Necrosis Factor Receptor Superfamily, Member 18 in 15 µg of Mouse Skeletal Muscle by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
- Detects 25 kDa.
Target Information
Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR, is encoded by the TNFRSF18 gene located at 1p36.33.
This receptor is part of the TNF-receptor superfamily and shows increased expression upon T-cell activation.
It plays a key role in immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells.
Knockout studies in mice suggest its involvement in regulation of CD3-driven T-cell activation and programmed cell death.
Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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