Thermo Fisher Scientific GITR (TNFRSF18) Monoclonal Antibody (T9P4G4-D7), FITC
GITR(TNFRSF18) 단백질 검출용 FITC 결합 마우스 모노클로날 항체. Western blot, IHC, ELISA 등에 사용 가능. 498/517 nm 형광 특성으로 세포 분석에 적합. 4°C 암소 보관, 연구용 전용 제품.
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Thermo Fisher Scientific GITR (TNFRSF18) Monoclonal Antibody (T9P4G4-D7), FITC
Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:1,000 | |
| Immunohistochemistry (IHC) | Assay-dependent | |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | T9P4G4-D7 |
| Immunogen | Synthetic peptide from the C-terminal of Human Tumor Necrosis Factor Receptor Superfamily, Member 18 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
A 1:1,000 dilution of MA5-45910 was sufficient for detection of Tumor Necrosis Factor Receptor Superfamily, Member 18 in 15 µg of Mouse Skeletal Muscle by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 25 kDa.
Target Information
Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR, is a protein encoded by the TNFRSF18 gene in humans. It is mapped to chromosome 1p36.33. This receptor shows increased expression upon T-cell activation and plays a key role in immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice suggest its role in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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