Thermo Fisher Scientific GITR (TNFRSF18) Monoclonal Antibody (T9P4G4-D7), APC
GITR(TNFRSF18) 단백질을 인식하는 APC 결합 마우스 단클론 항체. Western blot, IHC, ELISA 등에 사용 가능. 1 mg/mL 액상 형태로 제공되며 4°C에서 보관. T세포 활성화 및 면역 자가관용 연구에 적합.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific GITR (TNFRSF18) Monoclonal Antibody (T9P4G4-D7), APC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | T9P4G4-D7 |
| Immunogen | Synthetic peptide from the C-terminal of Human Tumor Necrosis Factor Receptor Superfamily, Member 18 |
| Conjugate | APC (Allophycocyanin) |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
A 1:1,000 dilution of MA5-45909 was sufficient for detection of Tumor Necrosis Factor Receptor Superfamily, Member 18 in 15 µg of Mouse Skeletal Muscle by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. Detects 25 kDa.
Target Information
Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR, is a protein encoded by the TNFRSF18 gene in humans (mapped to 1p36.33).
This gene encodes a member of the TNF-receptor superfamily. The receptor shows increased expression upon T-cell activation and plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells.
Knockout studies in mice suggest its role in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.