Thermo Fisher Scientific Prolactin Receptor (hPRL Receptor) Recombinant Rabbit Monoclonal Antibody (PRLR, 3785R)
Recombinant Rabbit Monoclonal Antibody targeting human Prolactin Receptor (PRLR). Validated for IHC (Paraffin). High specificity and reproducibility. Supplied as liquid, 200 µg/mL, Protein A/G purified, stored at 4°C.
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- 5618-RBM6-P0
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PRLR, 3785R |
| Immunogen | Recombinant full-length human PRLR protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For immunohistochemistry (PFA-fixed): incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Prolactin (PRL) is a pituitary hormone involved in milk production, salt and water regulation, growth, development, and reproduction. PRL acts through a signal transduction pathway initiated by binding to the transmembrane prolactin receptor (PRLR), a member of the cytokine receptor family. PRLR exists in multiple forms (short and long) depending on tissue and species, with molecular weights ranging from ~40 to 100 kDa. It consists of three domains: an extracellular region with five cysteines containing the prolactin binding site, a single transmembrane domain, and a cytoplasmic region influencing ligand binding and cellular function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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