Thermo Fisher Scientific Phospho-Histone H3 (Ser10) Recombinant Rabbit Monoclonal Antibody (HisH3S10-4B6), APC
APC 형광 표지된 재조합 토끼 단일클론 항체로, 인간 Histone H3 Ser10 인산화 형태를 특이적으로 인식합니다. Flow Cytometry에 적합하며 높은 특이성과 재현성을 제공합니다. Protein A/G로 정제되어 안정적인 품질을 유지합니다.
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Thermo Fisher Scientific Phospho-Histone H3 (Ser10) Recombinant Rabbit Monoclonal Antibody (HisH3S10-4B6), APC
Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HisH3S10-4B6 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser10 of human phospho histone H3 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745016 |
Additional Formats
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Histone H3 is a DNA-binding protein found in eukaryotic chromatin. It forms nucleosome structures with other core histones and plays a central role in transcription regulation, DNA repair, replication, and chromosomal stability.
Post-translational modifications such as methylation, acetylation, and phosphorylation affect chromatin structure and transcription factor binding. The N-terminal tail of H3 undergoes various modifications influencing cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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