Thermo Fisher Scientific TWIST2 Polyclonal Antibody
TWIST2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합합니다. 인간, 생쥐, 랫트 반응성이 있으며, 고순도 Affinity 정제 및 1 mg/mL 농도로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TWIST2 (Accession Q8WVJ9), corresponding to amino acid residues S10–S60 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2818326 |
Product Specific Information
Antibody detects endogenous levels of total Twist2.
Target Information
Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A, and MEF2C.
Also represses expression of proinflammatory cytokines such as TNFA and IL1B.
Involved in postnatal glycogen storage and energy metabolism.
Inhibits premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by altering internal signal transduction responses of osteoblasts to external growth factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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