Thermo Fisher Scientific RING1 Polyclonal Antibody
RING1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 ICC/IF에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 고순도의 Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며 -20°C에서 안정합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RING1 (Accession Q06587), corresponding to amino acid residues S212–I262 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818324 |
Product Specific Information
Antibody detects endogenous levels of total Ring1A.
Target Information
This gene belongs to the RING finger family, which encodes proteins containing a RING domain—a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex and interacts with BMI1, EDR1, and CBX4 proteins, colocalizing with them in large nuclear domains. Interaction with CBX4 occurs via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, contiguous with the RING finger genes FABGL and HKE4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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