Thermo Fisher Scientific OGDH Recombinant Rabbit Monoclonal Antibody (4O7N7)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

4O7N7

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 869-1023 of human OGDH (NP_002532.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OGDH,uniProtId:Q02218-1,ncbiNodeId:9606,antigenRange:869-1023,antigenLength:1023,antigenImageFileName:MA5-51260_OGDH_Q02218-1_Rabbit.svg,antigenImageFileNamePDP:MA5-51260_OGDH_Q02218-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.088 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_3094306

Product Specific Information

Immunogen sequence: RSSFDEMLPG THFQRVIPED GPAAQNPENV KRLLFCTGKV YYDLTRERKA RDMVGQVAIT RIEQLSPFPF DLLLKEVQKY PNAELAWCQE EHKNQGYYDY VKPRLRTTIS RAKPVWYAGR DPAAAPATGN KKTHLTELQR LLDTAFDLDV FKNFS

Target Information

This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitocondrial matrix and uses thiamine pyrophosphate as a cofactor. A congential deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.