Thermo Fisher Scientific OGDH Recombinant Rabbit Monoclonal Antibody (4O7N7)
OGDH 단백질을 인식하는 토끼 단클론 항체로, Western blot, IHC, ELISA에 사용 가능. 인간, 마우스, 랫트 반응성. HEK293 세포에서 발현된 재조합 항체이며, 고순도 친화 크로마토그래피로 정제됨. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 4O7N7 |
| Immunogen | Recombinant fusion protein containing amino acids 869–1023 of human OGDH (NP_002532.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.088 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3094306 |
Product Specific Information
Immunogen sequence:
RSSFDEMLPG THFQRVIPED GPAAQNPENV KRLLFCTGKV YYDLTRERKA RDMVGQVAIT RIEQLSPFPF DLLLKEVQKY PNAELAWCQE EHKNQGYYDY VKPRLRTTIS RAKPVWYAGR DPAAAPATGN KKTHLTELQR LLDTAFDLDV FKNFS
Target Information
This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex, which catalyzes the conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO₂ during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. Congenital deficiency in 2-oxoglutarate dehydrogenase activity may lead to hypotonia, metabolic acidosis, and hyperlactatemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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