Thermo Fisher Scientific GLP-2 Recombinant Rabbit Monoclonal Antibody (3K3P5)
GLP-2 단백질을 인식하는 재조합 토끼 단클론 항체로, IHC, ICC/IF, ELISA에 적합합니다. 높은 특이성과 감도를 제공하며, HEK293 발현 시스템에서 생산되었습니다. 액상 형태로 공급되며 -20°C에서 안정적으로 보관 가능합니다.
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Thermo Fisher Scientific GLP-2 Recombinant Rabbit Monoclonal Antibody (3K3P5)
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
- Immunocytochemistry (ICC/IF): 1:50–1:200
- ELISA: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3K3P5 |
| Immunogen | Synthetic peptide within amino acids 81–180 of human GLP-2 (P01275) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912010 |
Product Specific Information
- Target localization: Secreted
- Immunogen sequence:
TKRNRNNIAK RHDEFERHAE GTFTSDVSSY LEGQAAKEFI AWLVKGRGRR DFPEEVAIVE ELGRRHADGS FSDEMNTILD NLAARDFINW LIQTKITDRK
Target Information
Glucagon plays a key role in glucose metabolism and homeostasis. It regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. As a counterregulatory hormone of insulin, it raises plasma glucose levels in response to insulin-induced hypoglycemia. GLP-1 and GLP-2 have distinct physiological roles: GLP-1 stimulates glucose-dependent insulin release and suppresses plasma glucagon, while GLP-2 promotes intestinal growth and enhances nutrient absorption. GLP-2 increases villus height, crypt cell proliferation, and intestinal glucose transport while reducing mucosal permeability and enterocyte apoptosis. The gastrointestinal tract is the principal target of GLP-2 action, contributing to nutrient homeostasis and intestinal mucosal health.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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