Thermo Fisher Scientific Caveolin 3 Recombinant Rabbit Monoclonal Antibody (4G5W2)
Caveolin 3 단백질을 타겟으로 하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체(4G5W2). Western blot, IHC, ELISA 등에 사용 가능하며 인간, 마우스, 랫트 반응성. 액상 형태로 -20°C 보관, 연구용 전용.
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Thermo Fisher Scientific Caveolin 3 Recombinant Rabbit Monoclonal Antibody (4G5W2)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 4G5W2 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–151 of human Caveolin-3 (P56539) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912006 |
Product Specific Information
- Positive test controls include: Mouse lung, Mouse heart, Rat heart
- Target localization: Cell membrane, Golgi apparatus membrane, Membrane, Peripheral membrane protein, caveola
Immunogen sequence:
MMAEEHTDLE AQIVKDIHCK EIDLVNRDPK NINEDIVKVD FEDVIAEPVG TYSFDGVWKV SYTTFTVSKY WCYRLLSTLL GVPLALLWGF LFACISFCHI WAVVPCIKSY LIEIQCISHI YSLCIRTFCN PLFAALGQVC SSIKVVLRKE V
Target Information
Caveolin-3 (CAV3) acts as a scaffolding protein within the caveolar membrane. It interacts directly with G-protein alpha subunits and regulates their activity. Caveolin-3 also influences voltage-gated potassium channels and plays a key role in sarcolemma repair in skeletal muscle and cardiomyocytes. It mediates recruitment of CAVIN2 and CAVIN3 proteins to caveolae. Mutations in CAV3 can lead to HyperCKmia, rippling muscle disease 2, cardiomyopathy, long QT syndrome 9, sudden infant death syndrome, and myopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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