Thermo Fisher Scientific GLP-1 Recombinant Rabbit Monoclonal Antibody (1R1J8)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50 - 1:200

-

Immunocytochemistry (ICC/IF)

1:50 - 1:200

-

Product Specifications

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

1R1J8

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 70-150 of human GLP1 (P01275). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GLP-1,uniProtId:P01275-1,ncbiNodeId:9606,antigenRange:70-150,antigenLength:180,antigenImageFileName:MA5-42868_GLP-1_P01275-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42868_GLP-1_P01275-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.8 mg/mL

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2912009

Product Specific Information

The target is usually found in the following locations: Secreted.

Target Information

GCG is also known as GLP1, or Glucagon. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis.It is mapped to 2q36-2q37. GLP1, also known as 7-37 for the codons of the preproglucagon molecule which encode it, renders pancreatic beta-cells glucose-competent and may be useful in the treatment of noninsulin-dependent diabetes mellitus. Also, GLP1 is a potent insulin secretagogue.It plays a major role in the enteroinsular axis, accounting, for example, for the finding that plasma insulin levels accompanying oral intake of glucose are greater than those observed when glucose is given intravenously.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.