Thermo Fisher Scientific BAZ2A Polyclonal Antibody
Rabbit 유래의 BAZ2A 폴리클로날 항체로, ICC/IF 실험에 적합합니다. TIP5 항원을 면역원으로 사용하였으며, 인간 단백질에 특이적으로 반응합니다. 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관이 권장됩니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human TIP5 (BAZ2A, UniProt ID: Q9UIF9-1, amino acids 481–572) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Storage Conditions | Store at 4°C (short term). For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2665089 |
Product Specific Information
Immunogen sequence:
SLEVPLTASVT SPKASPVTSP AAAFPTASPA NKDVSSFLET TADVEEITGE GLTASGSGDV MRRRIATPEE VRLPLQHGWR REVRIKKGSH R
- Highest antigen sequence identity to orthologs: mouse 71%, rat 63%.
Target Information
TIP5 (BAZ2A) is the large subunit of the nucleolar remodeling complex (NoRC), responsible for repression of ribosomal gene transcription.
Histone deacetylation is involved in this repression, and TIP5 associates with histone deacetylase HDAC1 to mediate histone deacetylation near the rDNA promoter.
The interaction between TIP5 and HDAC1, essential for transcriptional repression, is mediated by the C-terminal PHD finger and bromodomain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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