Thermo Fisher Scientific BAZ2A Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human TIP5 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BAZ2A,uniProtId:Q9UIF9-1,ncbiNodeId:9606,antigenRange:481-572,antigenLength:1905,antigenImageFileName:PA5-66636_BAZ2A_Q9UIF9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-66636_BAZ2A_Q9UIF9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.7 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2665089

Product Specific Information

Immunogen sequence: SLEVPLTASVT SPKASPVTSP AAAFPTASPA NKDVSSFLET TADVEEITGE GLTASGSGDV MRRRIATPEE VRLPLQHGWR REVRIKKGSH R

Highest antigen sequence identity to the following orthologs - mouse 71%, rat 63%.

Target Information

TIP 5 is the large subunit of the nucleolar remodeling complex NoRC. NoRC causes the repression of ribosomal gene transcription. It was demonstrated that histone deacetylation is involved in this repression and that TIP5 is associated with the histone deacetylase HDAC1 and mediates the deacetylation of histones in the vicinity of the rDNA promoter. The interaction of TIP5 and HDAC1, which is necessary for transcriptional repression, is established by the C-terminal PHD finger and bromodomain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.