Thermo Fisher Scientific Coilin Monoclonal Antibody (1H10)

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5 µg/mL

-

Immunocytochemistry (ICC/IF)

5 µg/mL

-

Immunoprecipitation (IP)

2 µg

-

Product Specifications

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

1H10

Immunogen

Recombinant human protein purified from E.coli (His-Coilin)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2538728

Product Specific Information

A suggested positive control for this product is HeLa cell lysate.

Target Information

The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.