Thermo Fisher Scientific PTPRM Monoclonal Antibody (T5-AF1A8)
PTPRM 단백질을 인식하는 Mouse monoclonal 항체로 Western blot 및 Immunoprecipitation에 적합합니다. 세포 성장 및 신호전달 연구에 유용하며, 비접합(Unconjugated) 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution / Amount |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunoprecipitation (IP) | 1 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | T5-AF1A8 |
| Immunogen | Recombinant human protein purified from E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2538724 |
Product Specific Information
A suggested positive control for this product is Bosc23 cell lysate transfected with Myc/His/R-PTP mu.
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family, which regulates various cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This receptor-type PTP contains an extracellular region, a single transmembrane region, and two tandem catalytic domains. The extracellular region includes a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain, and four fibronectin type III-like repeats.
It mediates cell-cell aggregation through homophilic interaction and can interact with scaffolding protein RACK1/GNB2L1, which is essential for downstream signaling in response to cell-cell adhesion.
Alternative splicing results in multiple transcripts encoding distinct isoforms.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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