Thermo Fisher Scientific MCT2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 379-478 of human SLC16A7 (NP_0012575511) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MCT2,uniProtId:O60669-1,ncbiNodeId:9606,antigenRange:379-478,antigenLength:478,antigenImageFileName:PA5-88516_MCT2_O60669-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88516_MCT2_O60669-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.08 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804968

Product Specific Information

Positive Samples: HepG2, HL-60, Mouse kidney, Rat testis, Rat brain; Cellular Location: Cell membrane, Multi-pass membrane protein

Immunogen sequence: TIVECGPVLL GPPLAGKLVD LTGEYKYMYM SCGAIVVAAS VWLLIGNAIN YRLLAKERKE ENARQKTRES EPLSKSKHSE DVNVKVSNAQ SVTSERETNI

Target Information

Tissues with few or no mitochondria, such as erythrocytes and tumor cells, depend largely on glycolysis to generate ATP. The major end products of glycolysis, pyruvate and lactate, must be eliminated from these cells to enable continued glycolytic flux and prevent toxic effects. H+/monocarboxylate transporters mediate the transport of lactate and pyruvate. Human MCT2 has a high affinity for the transport of pyruvate.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.