Thermo Fisher Scientific Acid Phosphatase 1 Polyclonal Antibody
Thermo Fisher Scientific의 Acid Phosphatase 1 Polyclonal Antibody는 인간 및 생쥐 시료에 반응하며, Western blot, IHC, ELISA에 적합합니다. 친화 크로마토그래피로 정제된 비결합 항체로, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–158 of human ACP1 (NP_0090301) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804970 |
Product Specific Information
- Immunogen sequence:
MAEQATKSVL FVCLGNICRS PIAEAVFRKL VTDQNISENW VIDSGAVSDW NVGRSPDPRA VSCLRNHGIH TAHKARQITK EDFATFDYIL CMDESNLRDL NRKSNQVKTC KAKIELLGSY DPQKQLIIED PYYGNDSDFE TVYQQCVRCC RAFLEKAH - Positive Samples: Mouse liver
- Cellular Location: Cytoplasm
Target Information
Low molecular weight protein tyrosine phosphatases, including the human red cell phosphatase HCPTP, are widely expressed cytosolic proteins (~18 kDa) that exist in distinct isoforms and are highly selective for phosphotyrosine. HCPTP-A and HCPTP-B, expressed in human red cells and placenta, are fast and slow forms of red cell acid phosphatase. Like other tyrosine phosphatases, HCPTP is inhibited by vanadate and involves a cystinylphosphate intermediate in its catalytic mechanism. The crystal structure of bovine heart enzyme BHPTP reveals a four-stranded central β-sheet with flanking α-helices and an active-site cysteine residue typical of tyrosine phosphatases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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