Thermo Fisher Scientific Alpha Fetoprotein Polyclonal Antibody
마우스 AFP 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, ELISA, IP에 적합합니다. 합성 펩타이드(aa 50–100)를 면역원으로 제작되었으며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었고 -20°C에서 보관합니다.
- 카탈로그번호
- MAFP-101AP
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 50–100 on mouse alpha-fetoprotein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Alpha Fetoprotein (AFP) is a major plasma protein produced by the yolk sac, intestinal tract, and liver during fetal development. In adults, AFP expression is often associated with hepatoma or teratoma, though hereditary persistence can occur without pathology. AFP is considered the fetal counterpart of serum albumin, with both genes located tandemly on chromosome 4. It exists in monomeric, dimeric, and trimeric forms and can bind copper, nickel, fatty acids, and bilirubin. AFP levels in amniotic fluid are used to screen for neural tube defects such as spina bifida and anencephaly. Elevated serum AFP is observed in hepatocellular carcinoma, teratoblastoma, colorectal, pancreatic cancers, and germ cell tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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