Thermo Fisher Scientific Alpha Fetoprotein Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Target Information

Alpha Fetoprotein (AFP) is a major plasma protein produced by the yolk sac, intestinal tract, and liver during fetal development. In adults, AFP expression is often associated with hepatoma or teratoma, though hereditary persistence can occur without pathology. AFP is considered the fetal counterpart of serum albumin, with both genes located tandemly on chromosome 4. It exists in monomeric, dimeric, and trimeric forms and can bind copper, nickel, fatty acids, and bilirubin. AFP levels in amniotic fluid are used to screen for neural tube defects such as spina bifida and anencephaly. Elevated serum AFP is observed in hepatocellular carcinoma, teratoblastoma, colorectal, pancreatic cancers, and germ cell tumors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.