Thermo Fisher Scientific PIKFYVE Monoclonal Antibody (OTI1A5), TrueMAB
PIKFYVE 단백질을 인식하는 마우스 모노클로날 항체로, Western blot 및 IHC(Paraffin) 실험에 적합합니다. 무보존제, 동결건조 형태이며 PBS 버퍼에 trehalose 포함. 인간, 생쥐, 랫트 반응성. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A5 |
| Immunogen | Full length human recombinant protein of human PIKFYVE produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
PIKFYVE belongs to a large family of lipid kinases that modify the phosphorylation status of intracellular phosphatidylinositol.
PIKFYVE functions as the PtdIns(3,5)P2-producing component of a trimolecular complex that regulates endosomal membrane dynamics.
Other components include VAC14 (activator) and FIG4 (phosphatase).
PIKFYVE exhibits both phosphoinositide 5-kinase and protein kinase activities.
For a detailed review, see Shisheva.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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