Thermo Fisher Scientific FOXP1 Recombinant Rabbit Monoclonal Antibody (JF1017)
FOXP1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, Flow cytometry에 적합합니다. 높은 특이성과 민감도를 제공하며, 로트 간 일관성이 우수합니다. 단백질 A로 정제되었으며, 4°C 보관 및 -20°C 장기 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JF1017 |
| Immunogen | Synthetic peptide within human FOXP1 aa 615–653 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809800 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and expressed, and individual clones are screened to select optimal candidates.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the larger rabbit immune repertoire
Target Information
FOXP1 belongs to the forkhead box (FOX) transcription factor family, subfamily P. These transcription factors regulate tissue- and cell type-specific gene transcription during development and adulthood.
FOXP1 protein contains both DNA-binding and protein-protein interaction domains. It may function as a tumor suppressor, as it is lost in several tumor types and maps to chromosome region 3p14.1, which is associated with tumor suppressor genes.
Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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