Thermo Fisher Scientific NQO1 Recombinant Rabbit Monoclonal Antibody (JF440-1)
Thermo Fisher Scientific의 NQO1 Recombinant Rabbit Monoclonal Antibody (JF440-1)은 인간, 마우스, 랫트에 반응하며, WB, ICC/IF, Flow, IP에 적합합니다. 재조합 단클론 항체로 높은 특이성과 일관성을 제공하며, 장기 보관 시 -20°C에서 안정성을 유지합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:100 |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JF440-1 |
| Immunogen | Synthetic peptide within Human NQO1 (aa 1–49) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809805 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and functions as a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones, preventing the production of radical species.
Altered expression of NQO1 has been observed in various tumors and is associated with Alzheimer’s disease (AD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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