Thermo Fisher Scientific TG Monoclonal Antibody (OTI8E8), TrueMAB
인체 Thyroglobulin 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, WB 및 IHC(P) 적용 가능. Lyophilized 형태로 제공되며 PBS buffer에 trehalose 포함. 연구용으로만 사용 가능하며, 재구성 및 결합 실험에 적합.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8E8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 20–358 of human TG produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of ~1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells. It plays a central role in the uptake, incorporation, and biosynthesis of thyroid hormones T4 and T3.
Autoantibodies against hTg are associated with autoimmune thyroid diseases such as Hashimoto thyroiditis and Graves disease, with the highest levels observed in Hashimoto thyroiditis.
Anti-hTG is also characteristic of thyroid cancer and can be used for follow-up of cancer patients.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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