Thermo Fisher Scientific MTNR1B Polyclonal Antibody
Rabbit polyclonal antibody against human MTNR1B. Validated for IHC (P) and ELISA. High specificity with 100% identity to human and gorilla. Supplied as liquid, 1 mg/mL, purified by antigen affinity chromatography. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from C-terminal cytoplasmic domain of human MTNR1B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550395 |
Product Specific Information
- Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (89%)
- For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
- After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
This gene encodes one of two high-affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. The gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain, although detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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