Thermo Fisher Scientific FGF23 (Fibroblast Growth Factor 23) Monoclonal Antibody (FGF23/4171)
인간 FGF23 단백질을 인식하는 마우스 단클론 항체로, IHC(P), IHC(PFA), Peptide Array 등 다양한 응용에 적합합니다. 단백질 A/G로 정제된 액상 형태이며, PBS(pH 7.4)에 보존제 없이 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FGF23/4171 |
| Immunogen | Recombinant fragment (around aa25–251) of human FGF23 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in various biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion.
FGF23 inhibits renal tubular phosphate transport and is associated with autosomal dominant hypophosphatemic rickets, an inherited phosphate-wasting disorder. Abnormally high expression levels have been found in oncogenic hypophosphatemic osteomalacia, a disease caused by abnormal phosphate metabolism. Mutations in this gene can also cause familial tumoral calcinosis with hyperphosphatemia.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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