
Thermo Fisher Scientific FGF23 (Fibroblast Growth Factor 23) Monoclonal Antibody (FGF23/4162)
인간 FGF23 단백질을 인식하는 마우스 단클론 항체로, IHC(P), IHC(PFA), Peptide Array에 사용 가능. 단백질 A/G로 정제된 액상 형태이며, PBS(pH 7.4)에 보존제 없이 제공. -20°C 보관, 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Peptide Array (Array)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FGF23/4162 |
| Immunogen | Recombinant fragment (around aa25–251) of human FGF23 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in biological processes such as embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion.
FGF23 inhibits renal tubular phosphate transport. Mutations in this gene are associated with autosomal dominant hypophosphatemic rickets, an inherited phosphate-wasting disorder. Abnormally high expression levels are found in oncogenic hypophosphatemic osteomalacia, a disease characterized by abnormal phosphate metabolism. Mutations also cause familial tumoral calcinosis with hyperphosphatemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(본 제품 관련 항원 구조 이미지 및 단백질 영역 표시 이미지가 포함됩니다.)
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