Thermo Fisher Scientific IL1F9 Polyclonal Antibody
IL1F9 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, Flow Cytometry에 사용 가능. 인간 및 마우스 반응성. 고순도 Affinity chromatography 정제, -20°C 보관. 연구용으로 NF-κB 및 MAPK 경로 관련 염증 반응 연구에 적합.
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Thermo Fisher Scientific IL1F9 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Flow Cytometry (Flow) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human IL36G (Accession Q9NZH8), amino acids M1–Q32 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818755 |
Product Specific Information
Antibody detects endogenous levels of total IL1F9.
Target Information
IL1F9 (also known as IL-36γ) is a cytokine that binds and signals through the IL1RL2/IL-36R receptor, activating NF-κB and MAPK pathways.
It is part of the IL-36 signaling system involved in epithelial barrier inflammation and skin immune responses.
Acts on keratinocytes, dendritic cells, and T-cells to drive tissue infiltration, maturation, and proliferation.
Induces chemokine expression such as CCL3, CCL4, CCL5, CCL2, CCL17, CCL22, CXCL8, CCL20, and CXCL1, as well as TNF-α, S100A7/psoriasin, and iNOS.
May participate in neutrophilic airway inflammation and innate immune responses to fungal pathogens like Aspergillus fumigatus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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